Lifelong physical activity in maintaining bone strength in older men and women of the Age, Gene/environment susceptibility-reykjavik study

N. J. Rianon, T. F. Lang, Gunnar Sigurdsson, G. Eiriksdottir, S. Sigurdsson, M. Garcia, S. Pajala, A. Koster, B. Yu, B. J. Selwyn, W. C. Taylor, A. S. Kapadia, V. Gudnason, L. J. Launer, T. B. Harris

Rannsóknarafurð: Framlag til fræðitímaritsGreinritrýni

8 Tilvitnanir (Scopus)

Útdráttur

Summary We examined if lifelong physical activity is important for maintaining bone strength in the elderly. Associations of quantitative computerized tomography-acquired bone measures (vertebral and femoral) and self-reported physical activity in mid-life (mean age, 50 years), in old age (≥65 years), and throughout life (recalled during old age) were investigated in 2,110 men and 2,682 women in the AGES- Reykjavik Study. Results conclude lifelong physical activity with continuation into old age (≥65 years) best maintains better bone health later in life. Introduction Skeletal loading is thought to modulate the loss of bone in later life, and physical activity is a chief means of affecting bone strength by skeletal loading. Despite much discussion regarding lifelong versus early adulthood physical activity for preventing bone loss later in life, inconsistency still exists regarding how to maintain bone mass later in life (≥65 years). Methods We examined if lifelong physical activity is important for maintaining bone strength in the elderly. Results The associations of quantitative computerized tomography-acquired vertebral and femoral bone measuresand self-reported physical activity in mid-life (mean age, 50 years), in old age (≥65 years), and throughout life (recalled during old age) were investigated in 2,110 men and 2,682 women in the AGES-Reykjavik Study. Conclusion Our findings conclude that lifelong physical activity with continuation into old age (≥65 years) best maintains better bone health in the elderly.

Upprunalegt tungumálEnska
Síður (frá-til)2303-2312
Síðufjöldi10
FræðitímaritOsteoporosis International
Bindi23
Númer tölublaðs9
DOI
ÚtgáfustaðaÚtgefið - sep. 2012

Athugasemd

Funding Information:
The Age, Gene/Environment Susceptibility–Reykjavik Study is funded by NIH contract N01-AG-12100, the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament). Genotyping was conducted at the NIA IRP Laboratory of Neurogenetics.

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