Longitudinal immunological studies were performed in five patients with Bloom's syndrome. Serum IgG concentration showed no age-related increase. IgA levels were below the 10th percentile in childhood, but rose to normal in all but one. IgM was decreased in four patients at diagnosis and remained so in three ot them. Cellular immunity results were very variable, even within one patient. An immunologic attrition was not demonstrated.
|Fræðitímarit||Annales de Genetique|
|Útgáfustaða||Útgefið - 1991|