Etiology of Waldenström Macroglobulinemia: Genetic Factors and Immune-related Conditions

Elisabet E. Manasanch, Sigurdur Y. Kristinsson, Ola Landgren

Rannsóknarafurð: Framlag til fræðitímaritsGreinritrýni

7 Tilvitnanir (Scopus)

Útdráttur

Epidemiologic studies provide an insight into the etiology of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia, which indicates that repetitive immune stimulation and genetic factors play an important role. Here, the current understanding on the causes of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia are reviewed. Recent studies of the literature are discussed, and future population-based studies are proposed to further elucidate the molecular mechanisms that underlie these associations. Finally, the clinical implications of these data are outlined, and perspectives on clinical follow-up and counseling are provided.

Upprunalegt tungumálEnska
Síður (frá-til)194-197
Síðufjöldi4
FræðitímaritClinical Lymphoma, Myeloma and Leukemia
Bindi13
Númer tölublaðs2
DOI
ÚtgáfustaðaÚtgefið - apr. 2013

Athugasemd

Funding Information:
This research was supported by grants from the Swedish Cancer Society , Stockholm County Council , the Karolinska Institutet Foundations , and the Intramural Research Program of the National Institutes of Health , National Cancer Institute .

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