Vitamin D status of Icelandic children and its influence on bone accrual

Haukur Heidar Hauksson, Hannes Hrafnkelsson, Kristjan Thor Magnusson, Erlingur Johannsson, Emil L. Sigurðsson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The importance of vitamin D for children’s bone health has been well established, but the effects of less severe deficiency are not fully known. The main objective of this study was to assess the vitamin D status of Icelandic children at the age of 7, and again at 9 years of age, and the association of vitamin D status with bone mineral content and bone accrual over 2 years. We invited 321 children to participate in this study, and 267 (83 %) took part; 211 (79 %) underwent a DXA scan and 164 were again scanned 2 years later; 159 (60 %) vitamin D samples were measured and 119 (75 %) were measured again 2 years later. At age 7, 65 % of the children had vitamin D concentrations <50 nmol/l, and at age 9 this figure was 60 %. At age 7, 43 % of the children had insufficient amounts of vitamin D (37.5–50 nmol/l), and 22 % had a vitamin D deficiency (<37.5 nmol/l). In linear regression analysis, no association was found between vitamin D and bone mineral content. Furthermore, there was no significant difference in bone accrual over 2 years for the children with insufficient or deficient vitamin D at both ages, compared to those having more than 50 nmol/l at both time points. More than 60 % of Icelandic children have inadequate concentrations of vitamin D in serum repeatedly over a 2-year interval. However, vitamin D in the range did not have a significant effect on bone mineral content or accrual at ages 7 and 9.

Original languageEnglish
Pages (from-to)580-586
Number of pages7
JournalJournal of Bone and Mineral Metabolism
Volume34
Issue number5
DOIs
Publication statusPublished - 1 Sept 2016

Bibliographical note

Publisher Copyright:
© 2015, The Japanese Society for Bone and Mineral Research and Springer Japan.

Other keywords

  • 25(OH)-D
  • BMC
  • Bone accrual
  • Children
  • Vitamin D

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