Throat infections are associated with exacerbation in a substantial proportion of patients with chronic plaque psoriasis

Ragna Hlin Thorleifsdottir*, Jenna H. Eysteinsdottir, Jon H. Olafsson, Martin I. Sigurdsson, Andrew Johnston, Helgi Valdimarsson, Bardur Sigurgeirsson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)


Streptococcal throat infections are known to trigger or exacerbate psoriasis, and several studies support the benefit of tonsillectomy. To evaluate the potential of tonsillectomy as a treatment, we used a retrospective study-specific questionnaire to assess the proportion of psoriasis patients with sore throat-associated psoriasis exacerbations. Our survey sampled 275 psoriasis patients. Of patients with plaque psoriasis, 42% reported sore throat-associated psoriasis exacerbations, and of patients with confirmed streptococcal infections, 72% reported aggravation. Notably, women and patients with early onset psoriasis were more likely to report psoriasis exacerbation after a sore throat (p < 0.001, p = 0.046, respectively). Other psoriasis aggravation factors were more common in patients with sore throat-associated exacerbations (p < 0.01). Of tonsillectomized patients, 49% reported subsequent improvement and had more frequent sore throat-associated aggravation of psoriasis than patients who did not improve after tonsillectomy (p = 0.015). These findings suggest a closer association between sore throats, streptococcal throat infections and plaque psoriasis than reported previously.

Original languageEnglish
Pages (from-to)788-791
Number of pages4
JournalActa Dermato-Venereologica
Issue number6
Publication statusPublished - Sept 2016

Bibliographical note

Publisher Copyright:
© 2016 The Authors.

Other keywords

  • Chronic plaque psoriasis
  • Sore throat
  • Streptococcal throat infections
  • Tonsillectomy


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