The rise of carbapenem resistance in Europe: Just the tip of the iceberg

Ears-Net Coordination Group, EARS-Net participants

Research output: Contribution to journalLetterpeer-review

56 Citations (Scopus)


The European Antimicrobial Resistance Surveillance Network (EARS-Net) collects data on carbapenem resistance from invasive bacterial infections. Increasing percentages of carbapenem resistance in K. pneumoniae isolates were reported from progressively more countries in Europe between 2005 and 2010. A trend analysis showed increasing trends for Greece, Cyprus, Hungary and Italy (p < 0.01). EARS-Net collects data on invasive bacterial isolates, which likely correspond to a fraction of the total number of infections. Increasing reports of community cases suggest that dissemination of carbapenem-resistant K. pneumoniae has penetrated into the community. Good surveillance and infection control measures are urgently needed to contain this spread.

Original languageEnglish
Article number6
JournalAntimicrobial Resistance and Infection Control
Issue number1
Publication statusPublished - 2013

Bibliographical note

Publisher Copyright:
© 2013 Magiorakos et al.

Other keywords

  • Antimicrobial drug resistance
  • Carbapenems
  • Europe
  • Gram-negative bacteria
  • Klebsiella infections
  • β-Lactamases


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