TY - JOUR
T1 - The rise of carbapenem resistance in Europe
T2 - Just the tip of the iceberg
AU - Ears-Net Coordination Group
AU - EARS-Net participants
AU - Magiorakos, Anna Pelagia
AU - Suetens, Carl
AU - Monnet, Dominique L.
AU - Gagliotti, Carlo
AU - Heuer, Ole E.
AU - Apfalter, P.
AU - Goossens, M.
AU - Velinov, T.
AU - Maikanti-Charalambous, P.
AU - Zemlickova, H.
AU - Hammerum, A. M.
AU - Ivanova, M.
AU - Jalava, J.
AU - Coignard, B.
AU - Noll, I.
AU - Polemis, M.
AU - Tóth,
AU - Kristinsson, K. G.
AU - Cunney, R.
AU - Pantosti, A.
AU - Balode, A.
AU - Miciuleviciene, J.
AU - Perrin, M.
AU - Borg, M.
AU - van de Sande, N.
AU - Simonsen, G. S.
AU - Hryniewicz, W.
AU - Caniça, M.
AU - Codita, I.
AU - Kolman, J.
AU - Cuevas, O.
AU - Olsson-Liljequist, B.
AU - Blackburn, R.
N1 - Publisher Copyright:
© 2013 Magiorakos et al.
PY - 2013
Y1 - 2013
N2 - The European Antimicrobial Resistance Surveillance Network (EARS-Net) collects data on carbapenem resistance from invasive bacterial infections. Increasing percentages of carbapenem resistance in K. pneumoniae isolates were reported from progressively more countries in Europe between 2005 and 2010. A trend analysis showed increasing trends for Greece, Cyprus, Hungary and Italy (p < 0.01). EARS-Net collects data on invasive bacterial isolates, which likely correspond to a fraction of the total number of infections. Increasing reports of community cases suggest that dissemination of carbapenem-resistant K. pneumoniae has penetrated into the community. Good surveillance and infection control measures are urgently needed to contain this spread.
AB - The European Antimicrobial Resistance Surveillance Network (EARS-Net) collects data on carbapenem resistance from invasive bacterial infections. Increasing percentages of carbapenem resistance in K. pneumoniae isolates were reported from progressively more countries in Europe between 2005 and 2010. A trend analysis showed increasing trends for Greece, Cyprus, Hungary and Italy (p < 0.01). EARS-Net collects data on invasive bacterial isolates, which likely correspond to a fraction of the total number of infections. Increasing reports of community cases suggest that dissemination of carbapenem-resistant K. pneumoniae has penetrated into the community. Good surveillance and infection control measures are urgently needed to contain this spread.
KW - Antimicrobial drug resistance
KW - Carbapenems
KW - Europe
KW - Gram-negative bacteria
KW - Klebsiella infections
KW - β-Lactamases
UR - http://www.scopus.com/inward/record.url?scp=84883197445&partnerID=8YFLogxK
U2 - 10.1186/2047-2994-2-6
DO - 10.1186/2047-2994-2-6
M3 - Letter
AN - SCOPUS:84883197445
SN - 2047-2994
VL - 2
JO - Antimicrobial Resistance and Infection Control
JF - Antimicrobial Resistance and Infection Control
IS - 1
M1 - 6
ER -