The evolution of molecular biology into systems biology

Hans V. Westerhoff*, Bernhard O. Palsson

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

359 Citations (Scopus)

Abstract

Systems analysis has historically been performed in many areas of biology, including ecology, developmental biology and immunology. More recently, the genomics revolution has catapulted molecular biology into the realm of systems biology. In unicellular organisms and well-defined cell lines of higher organisms, systems approaches are making definitive strides toward scientific understanding and biotechnological applications. We argue here that two distinct lines of inquiry in molecular biology have converged to form contemporary systems biology.

Original languageEnglish
Pages (from-to)1249-1252
Number of pages4
JournalNature Biotechnology
Volume22
Issue number10
DOIs
Publication statusPublished - Oct 2004

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