Study of the humoral response of Atlantic salmon (Salmo salar L.), naturally infected with Aeromonas salmonicida ssp. achromogenes

B. Magnadóttir*, S. Gudmundsdóttir, B. K. Gudmundsdóttir

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

The humoral antibody response of healthy Atlantic salmon and of two groups of salmon, naturally infected with Aeromonas salmonicida spp. achromogenes, was examined in some detail. One diseased group was chronically infected and the other recently infected. It was found that the humoral response of these two infected groups was quite different. The chronically infected fish showed poor specific response to the causative agent whereas the recently infected salmon produced strong specific antibody response. The chronically infected fish showed evidence of increased unspecific response including an elevated level of natural antibodies. The specific humoral response of the recently infected fish was primarily directed against two cell-associated antigens of the A. salmonicida spp. achromogenes bacterium, the A-layer protein and the o-polysaccharide component of LPS. In the chronically infected fish the humoral response was primarily directed against the A-layer protein.

Original languageEnglish
Pages (from-to)127-142
Number of pages16
JournalVeterinary Immunology and Immunopathology
Volume49
Issue number1-2
DOIs
Publication statusPublished - Nov 1995

Bibliographical note

Funding Information:
We wish to thankt hed irectorso f Fiskeldi,G rindavika ndI spor,P orllkshofn,I celand, for supplyingt he salmon.T his work was partially supportedb y a grant from the IcelandicR esearchC ouncil.

Other keywords

  • Aeromonas salmonicida spp. achromogenes
  • Humoral response
  • Natural infection
  • Salmo salar L.
  • Salmon

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