Pseudoprolapse of the anterior leaflet in chronic ischemic mitral regurgitation: identification and repair.

Sabet W Hashim, Samuel J Youssef, Bassem Ayyash, Anthony J Rousou, Sigurdur Ragnarsson, Susan Collazo, Arnar Geirsson

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Recurrence rates as high as 30% have been observed 6 months after treatment of chronic ischemic mitral regurgitation (CIMR) with isolated annuloplasty. We postulated that the high early recurrence rates resulted from the presence of untreated pseudoprolapse of the anterior leaflet. We conducted a retrospective study of all mitral valve repairs for CIMR performed by a single surgeon (S.W.H.) from 1995 to 2011. After annuloplasty, Gore-Tex neochordae were added if the high-pressure saline test indicated the presence of pseudoprolapse of the anterior leaflet. A total of 47 patients underwent mitral valve repair for CIMR. Of the 47 patients, 24 (51%) were found to have pseudoprolapse requiring the addition of neochordae. For all patients, the average age was 65.1 years, and 65.2% were men. Fourteen (30%) had had a preoperative intra-aortic balloon pump placed by cardiologists. Fourteen (30%) had severe pulmonary hypertension. Concomitant coronary artery bypass grafting was performed in 40 patients, with an average of 2.2 grafts; 7 had previously undergone coronary artery bypass grafting. Mitral Carpentier-Edwards physio annuloplasty rings were used in all patients with a mean size of 29 mm. One patient died postoperatively. Follow-up data were available for all 47 patients at an average of 4.9 years. The 5-year survival rate was 82.5%. The mean pre- and postoperative New York Heart Association class, ejection fraction, and mitral regurgitation grade were 3 and 1.52 (P < .0001), 34% and 41% (P = .0006), and 3.51 and 1.08 (P < .0001), respectively. Two patients developed greater than moderate mitral regurgitation. Effective repair of CIMR should include surgical techniques to correct pseudoprolapse of the anterior leaflet, when present. The selective addition of Gore-Tex neochordae to an undersized annuloplasty nearly eliminates recurrent regurgitation after mitral valve repair for CIMR.
Original languageEnglish
JournalJournal of Thoracic and Cardiovascular Surgery
Publication statusPublished - Apr 2012

Other keywords

  • Aged
  • Chronic Disease
  • Connecticut
  • Coronary Artery Bypass
  • Echocardiography, Transesophageal
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Mitral Valve
  • Mitral Valve Annuloplasty
  • Mitral Valve Insufficiency
  • Mitral Valve Prolapse
  • Myocardial Ischemia
  • Predictive Value of Tests
  • Recurrence
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome


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