P50 and P300 Event Related Potentials in Patients with Schizophrenia Recorded from High-Density EEG

Ovidiu C. Banea*, Elena Pegolo, Sara Marcu, Rún Friðriksdóttir, Eysteinn Ívarsson, Aron D. Jónasson, Viktor D. Jónasson, Brynja B. Magnusdóttir, Magnús Haraldsson, Eric Wassermann, Paolo Gargiulo

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

The main objectives of this study were to describe P50 and P300 cortical topography in patients with schizophrenia and to define a robust methodology of signal quantification using high density EEG. Within a clinical trial in which patients with schizophrenia and auditory verbal hallucinations were submitted to 10 days rTMS treatment, P50 and P300 were investigated as possible neurophysiological measurements to assess treatment effectiveness together with psychometric scales like Psychotic symptom rating scale (PSYRATS), depression, anxiety and stress scale (DASS) and Quality of Life scale (QoL). Here we describe the technique of collecting P50 and P300 using high-density EEG and we reproduce the preliminary data of P300 in one healthy subject and P50 in two patients and two healthy subjects.

Original languageEnglish
Title of host publication15th Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019 - Proceedings of MEDICON 2019
EditorsJorge Henriques, Paulo de Carvalho, Nuno Neves
PublisherSpringer
Pages1071-1077
Number of pages7
ISBN (Print)9783030316341
DOIs
Publication statusPublished - 2020
Event15th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2019 - Coimbra, Portugal
Duration: 26 Sept 201928 Sept 2019

Publication series

NameIFMBE Proceedings
Volume76
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Conference

Conference15th Mediterranean Conference on Medical and Biological Engineering and Computing, MEDICON 2019
Country/TerritoryPortugal
CityCoimbra
Period26/09/1928/09/19

Bibliographical note

Publisher Copyright:
© 2020, Springer Nature Switzerland AG.

Other keywords

  • High-density EEG
  • P300
  • P50
  • Schizophrenia

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