Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis

A. Love, R. Rydbeck, G. Utter, C. Orvell, K. Kristensson, E. Norrby

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.

Original languageEnglish
Pages (from-to)220-222
Number of pages3
JournalJournal of Virology
Volume58
Issue number1
DOIs
Publication statusPublished - 1986

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