Metabolic systems biology

Bernhard Palsson*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

72 Citations (Scopus)


The first full genome sequences were established in the mid-1990s. Shortly thereafter, genome-scale metabolic network reconstructions appeared. Since that time, we have witnessed an exponential growth in their number and uses. Here I discuss, from a personal point of view, four topics: (1) the placement of metabolic systems biology in the context of broader scientific developments, (2) its foundational concepts, (3) some of its current uses, and (4) some of the expected future developments in the field.

Original languageEnglish
Pages (from-to)3900-3904
Number of pages5
JournalFEBS Letters
Issue number24
Publication statusPublished - 17 Dec 2009

Other keywords

  • Metabolism
  • Systems biology


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