Medication of older people admitted to acute care -

Introduction: The Inter RAI Minimal Data Set for Acute Care (MDS-AC) is a geriatric assessment tool designed for use in acute medicine care. We used data from a study on the MDS-AC to evaluate the medication use of 75+ year old patients (n=730) admitted to selected acute care hospitals in five Nordic countries. Associations of medication use with: Preadmission Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Cognitive Performance Scale (CPS) , walking, memory, continence, falls, chronic pain, admission delirium, length of stay in hospital (LOS) and 12 months survival after discharge, were analyzed. Special focus was on polyphamacy, inappropriate medications, psychotropic medication use and cardiovascular medications. Results: Average number of drugs was 6.2(SD+/-3.7). Polypharmacy (five or more medications) was found among 66% of patients and 16% used inappropriate medications. Women used on average more medications than men, 6.6 vs 5.7 respectively (p < .05). Polypharmacy was associated with worse IADL function and pain (p<.001) and better cognitive function and less falls (p < .05). Inappropriate medications were associated to increased length of stay (p<.05). Psychotropic medications had the most pronounced association with worse function and outcomes in a variety of variables. Cardiovascular drugs were associated with better functional outcome. Conclusion: Polypharmacy, use of inappropriate medications and psychotropic medication use were prevalent in this study. Associations were found between these factors and negative functional outcomes. Individual tailoring of pharmacotherapy of acutely ill older patients with concomitant chronic illnesses combined with functional impairment is important.