Iron status in 6-y-old children: Associations with growth and earlier iron status

B. S. Gunnarsson*, I. Thorsdottir, G. Palsson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Objective: To investigate the iron status of 6-y-old children and its association with growth and earlier iron status. Design: In a cross-sectional study, children's body size measurements were recorded and blood samples taken near their sixth birthday. Subjects: A sample of 188 children, randomly selected in two previous studies, was contacted, and 139(74%) agreed to participate. Results: No children had iron deficiency anaemia, one was iron-deficient (serum ferritin (SF) <15 μg/l and mean corpuscular volume (MCV) <76) fl but 16% had depleted iron stores (SF<15μg /l). Iron status indices were generally higher than at 1 and 2y, but correlation was seen between iron status indices at 6y and earlier values. Haemoglobin concentration at 6y was negatively associated with length gain from birth to 1y (B±s.e.=-1.269±0.452; P=0.007; adj. R2=0.119) (n=52), and proportional weight gain from birth to 1y was higher among children with SF<15μg/l at 6y (295±33%; n=10) than those with SF≥15 μg/l (258±31%; n=49) (P=0.001). MCV at 2y predicted weight gain from 2 to 6y (B±s.e.=1.721±0.581; P=0.005; adj. R2=0.153)(n=44); also, children with SF<15μg/l at 6y (n=9) gained 7.8±1.2kg from 2 to 6y, while children with SF≥15 μg/l (n=35) gained 9.6±2.8 kg (P=0.007), furthermore a difference was seen in proportional weight gain from 2 to 6y between children with depleted iron stores at 2y and not, or 156±13 vs 169±18% (P=0.038). Conclusions: The results suggest that low iron status at 1 and 2y might lead to slower growth up to 6y of age. Low iron status at 1 and 2y and/or slower growth from 1 and 2y up to 6y might contribute to worse iron status at 6y, while faster growth in early childhood is related to lower iron status.

Original languageEnglish
Pages (from-to)761-767
Number of pages7
JournalEuropean Journal of Clinical Nutrition
Volume59
Issue number6
DOIs
Publication statusPublished - Jun 2005

Other keywords

  • Depleted iron stores
  • Growth
  • Haemoglobin (Hb)
  • Iron deficiency
  • Mean corpuscular volume (MCV)
  • Serum ferritin (SF)

Fingerprint

Dive into the research topics of 'Iron status in 6-y-old children: Associations with growth and earlier iron status'. Together they form a unique fingerprint.

Cite this