Influence of dietary cod liver oil on fatty acid composition of plasma lipids in human male subjects after myocardial infarction

G. V. SKÚLADÓTTIR*, E. GUDMUNDSDÓTTIR, E. ÓLAFSDÓTTIR, T. V. GUDMUNDSSON, T. HARDARSON, KRISTINSSON, Hanna S. Ásvaldsdóttir, S. P. SNORRASON, S. GUDBJARNASON

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Abstract. A randomized crossover study was carried out to investigate the fatty acid profile and concentrations of plasma lipids in male patients with myocardial infarction (MI) who supplemented their diet with 20 ml cod liver oil daily for 6 weeks. Subjects were divided into two groups, A and B. Group A received cod liver oil daily for 6 weeks after hospital discharge, but none for the subsequent 6 weeks. Group B did not start taking cod liver oil until 6 weeks after hospital discharge, and they then took cod liver oil for 6 weeks. Diet, medication or smoking habits were kept as constant as possible during the study. During the period of cod liver oil intake, eicosapentaenoic acid (20:5 (n‐3), EPA) and docosahexaenoic acid (22:6 (n‐3), DHA) increased significantly in phospholipids (PL), triglycerides (TG) and cholesterol esters (CE), whereas linoleic acid (18:2 (n‐6), LA), dihomo‐gamma‐linolenic acid (20:3 (n‐6), DHGLA) and arachidonic acid (20:4 (n‐6), AA) were significantly decreased in phospholipids. The plasma level of TG was significantly decreased during the cod liver oil intake. Total cholesterol, high density lipoprotein (HDL) cholesterol, and levels of apolipoproteins A1 and B were not affected by cod liver oil in these MI patients. 1990 Blackwell Publishing Ltd

Original languageEnglish
Pages (from-to)563-568
Number of pages6
JournalJournal of Internal Medicine
Volume228
Issue number6
DOIs
Publication statusPublished - Dec 1990

Other keywords

  • apolipoproteins
  • cod liver oil
  • fatty acids
  • HDL cholesterol
  • myocardial infarction
  • plasma cholesterol ester

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