In frame deletion of intron 7 in the p53 gene in a human tonsil tumor

Kristinn Pétur Magnússon; Z. Berke; E. Munck-Wikland; I. Lewensohn-Fuchs; G. Klein; T. Dallianas; K. G. Wiman

doi:10.3892/ijo.6.1.27

In frame deletion of intron 7 in the p53 gene in a human tonsil tumor

Kristinn Pétur Magnússon^*, Z. Berke, E. Munck-Wikland, I. Lewensohn-Fuchs, G. Klein, T. Dallianas, K. G. Wiman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.

Original language	English
Pages (from-to)	27-29
Number of pages	3
Journal	International Journal of Oncology
Volume	6
Issue number	1
DOIs	https://doi.org/10.3892/ijo.6.1.27
Publication status	Published - 1995
Externally published	Yes

Other keywords

human tonsil tumor
intron deletion
p53 gene mutation

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10.3892/ijo.6.1.27

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abstract = "We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.",

keywords = "human tonsil tumor, intron deletion, p53 gene mutation",

author = "Magn{\'u}sson, {Kristinn P{\'e}tur} and Z. Berke and E. Munck-Wikland and I. Lewensohn-Fuchs and G. Klein and T. Dallianas and Wiman, {K. G.}",

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AU - Magnússon, Kristinn Pétur

AU - Berke, Z.

AU - Munck-Wikland, E.

AU - Lewensohn-Fuchs, I.

AU - Klein, G.

AU - Dallianas, T.

AU - Wiman, K. G.

PY - 1995

Y1 - 1995

N2 - We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.

AB - We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.

KW - human tonsil tumor

KW - intron deletion

KW - p53 gene mutation

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U2 - 10.3892/ijo.6.1.27

DO - 10.3892/ijo.6.1.27

M3 - Article

AN - SCOPUS:0028917770

SN - 1019-6439

VL - 6

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EP - 29

JO - International Journal of Oncology

JF - International Journal of Oncology

IS - 1

ER -

In frame deletion of intron 7 in the p53 gene in a human tonsil tumor

Abstract

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