Gastric reflux is a significant causative factor of tooth erosion

W. P. Holbrook, J. Furuholm, K. Gudmundsson, A. Theodórs, J. H. Meurman

Research output: Contribution to journalArticlepeer-review


Dental erosion is caused by dietary or gastric acid. This study aimed to examine the location and severity of tooth erosion with respect to causative factors, and to determine whether the clinical pattern of erosion reflected the dominant etiological factor. The study involved 249 Icelandic individuals and included: a detailed medical history; clinical oral examination; salivary sampling, and analysis for flow rate, pH, and buffering capacity. Reflux was assessed in 91 individuals by gastroscopy, esophageal manometry, and 24-hour esophageal-pH monitoring. Reflux symptoms were reported by 36.5% individuals. Manometry results were abnormal in 8% of study participants, abnormal esophageal pH in 17.7%, and a pathological 24-hour pH recording in 21.3%. 3.6% were positive for Helicobacter pylori. Normal salivary flow was found in 92%, but low salivary buffering (10.4%) was associated with erosion into dentin (P < 0.05). Significant associations were found between erosion and diagnosed reflux disease (OR 2.772; P < 0.005) and daily consumption of acidic drinks (OR 2.232; P < 0.005).

Original languageEnglish
Pages (from-to)422-426
Number of pages5
JournalJournal of Dental Research
Issue number5
Publication statusPublished - 1 May 2009

Other keywords

  • Dental erosion
  • Gastro-esophageal reflux
  • Location
  • Risk factors
  • Saliva


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