Fungal meningitis

M. Gottfredsson, J. R. Perfect*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

94 Citations (Scopus)

Abstract

Fungi provide many benefits to humans. However, some of these fungi have the ability to become human pathogens. All the major fungal pathogens can produce meningitis. From the common cryptococcal meningitis to the rare fungal meningitis caused by a dimorphic or filamentous fungus, medical issues are discussed in this review on a fungus-specific basis. Both primary (Cryptococcus, Blastomyces, Histoplasma, Coccidioides, and other dimorphic fungi) and secondary (Aspergillus, Candida, and a series of molds) fungal pathogens can produce life-threatening central nervous system infections. These infections require immediate and precise diagnosis and carefully selected management strategies to optimize outcomes. In this review, we examine the epidemiology, pathogenesis, clinical manifestations, and treatment for fungal meningitis in all the major fungal groups.

Original languageEnglish
Pages (from-to)307-322
Number of pages16
JournalSeminars in Neurology
Volume20
Issue number3
DOIs
Publication statusPublished - 2000

Other keywords

  • Central nervous system infections
  • Fungi
  • Meningitis

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