TY - JOUR
T1 - Extracellular calcium protects isolated rat hepatocytes from injury
AU - Fariss, Marc W.
AU - Olafsdottir, Kristin
AU - Reed, Donald J.
PY - 1984/5/31
Y1 - 1984/5/31
N2 - The incubation of isolated rat hepatocytes in calcium-free medium resulted in a pronounced increase in lipid peroxidation, mitochondrial and cytoplasmic glutathione depletion, glutathione disulfide formation and efflux of reduced gluathione as compared with hepatocytes incubated in calcium containing medium. These data suggest that extracellular calcium ions serve a protective role in isolated rat hepatocytes against cell injury.
AB - The incubation of isolated rat hepatocytes in calcium-free medium resulted in a pronounced increase in lipid peroxidation, mitochondrial and cytoplasmic glutathione depletion, glutathione disulfide formation and efflux of reduced gluathione as compared with hepatocytes incubated in calcium containing medium. These data suggest that extracellular calcium ions serve a protective role in isolated rat hepatocytes against cell injury.
UR - http://www.scopus.com/inward/record.url?scp=0021259203&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(84)90693-4
DO - 10.1016/0006-291X(84)90693-4
M3 - Article
C2 - 6732796
AN - SCOPUS:0021259203
SN - 0006-291X
VL - 121
SP - 102
EP - 110
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 1
ER -