Effects of endotoxin and cytokines on lipid metabolism

Ingibjörg Harðardóttir, Carl Grunfeld, Kenneth R. Feingold*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

266 Citations (Scopus)


Endotoxin, via cytokines, induces marked changes in lipid metabolism: serum VLDL increases, whereas the effect on LDL levels varies among species. The increase in VLDL is caused by stimulation of hepatic VLDL secretion or inhibition of clearance, or both. These alterations can have deleterious or beneficial effects.

Original languageEnglish
Pages (from-to)207-215
Number of pages9
JournalCurrent Opinion in Lipidology
Issue number3
Publication statusPublished - 1994


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