Daily Events Are Associated With a Secretory Immune Response to an Oral Antigen in Men

Arthur A. Stone*, John M. Neale, Donald S. Cox, Anthony Napoli, Heiddis Valdimarsdottir, Eileen Kennedy-Moore

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

134 Citations (Scopus)


To examine a hypothesized link between daily stressful events and secretory immunoglobulin A (sIgA) antibody, 96 adults from the community completed daily event questionnaires and gave daily saliva samples for up to 12 weeks. They also ingested a capsule of a novel protein to challenge their secretory immune systems. The questionnaire yielded measures of negative and positive experiences, of their content, and of negative and positive affect. On a within-subjects, day-to-day basis, reporting more desirable events was related to more sIgA antibody, and reporting more undesirable events was related to less. Desirable events also had lagged (1 and 2 days), positive effects on sIgA levels. Undesirable work events and desirable leisure and household events were more strongly related to sIgA than events in other categories. Positive affect related directly to sIgA, and negative mood related inversely to same-day sIgA.

Original languageEnglish
Pages (from-to)440-446
Number of pages7
JournalHealth Psychology
Issue number5
Publication statusPublished - Sep 1994

Other keywords

  • daily events
  • immunology
  • lagged relations
  • secretory immunoglobulin A


Dive into the research topics of 'Daily Events Are Associated With a Secretory Immune Response to an Oral Antigen in Men'. Together they form a unique fingerprint.

Cite this