Correlated pedigree and molecular estimates of inbreeding and their ability to detect inbreeding depression in the Icelandic sheepdog, a recently bottlenecked population of domestic dogs

Gudbjörg Á Ólafsdóttir, Theódór Kristjánsson

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23 Citations (Scopus)

Abstract

We examine the relationship of the inbreeding coefficient (f) and molecular estimates of inbreeding (IR, sMLH) in the Icelandic sheepdog. The breed experienced a severe genetic bottleneck and near extinction in the last century. Molecular estimates and the inbreeding coefficient are significantly correlated despite the moderate number of markers and individuals used in this study. This is most likely an effect of the extreme relatedness and relatively high variance in individual inbreeding coefficients in the population. There is a significant relationship between inbreeding (f) and the occurrence of hip dysplasia. However, the molecular measures did not detect hip dysplasia as an inbreeding effect.

Original languageEnglish
Pages (from-to)1639-1641
Number of pages3
JournalConservation Genetics
Volume9
Issue number6
DOIs
Publication statusPublished - Dec 2008

Bibliographical note

Funding Information:
Acknowledgements We would like to thank the Icelandic sheepdog unit at the Icelandic Kennel Club for providing pedigree data, hip dysplasia records and assisting with DNA sampling. Thanks to Pro-karia ehf for help with laboratory work. This work was supported by the Icelandic Council for Genetic Resources in Agriculture.

Other keywords

  • Canis familiaris
  • Heterozygosity fitness correlations
  • Inbreeding
  • Multilocus heterozygosity

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