An internationally standardised antisaccade protocol

Chrystalina Antoniades, Ulrich Ettinger, Bertrand Gaymard, Iain Gilchrist, Arni Kristjánsson, Christopher Kennard, R. John Leigh, Imran Noorani, Pierre Pouget, Nikolaos Smyrnis, Adam Tarnowski, David S. Zee, R. H.S. Carpenter*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

91 Citations (Scopus)


Detailed measurements of saccadic latency - the time taken to make an eye movement to a suddenly-presented visual target - have proved a valuable source of detailed and quantitative information in a wide range of neurological conditions, as well as shedding light on the mechanisms of decision, currently of intense interest to cognitive neuroscientists. However, there is no doubt that more complex oculomotor tasks, and in particular the antisaccade task in which a participant must make a saccade in the opposite direction to the target, are potentially more sensitive indicators of neurological dysfunction, particularly in neurodegenerative conditions. But two obstacles currently hinder their widespread adoption for this purpose. First, that much of the potential information from antisaccade experiments, notably about latency distribution and amplitude, is typically thrown away. Second, that there is no standardised protocol for carrying out antisaccade experiments, so that results from one laboratory cannot easily be compared with those from another. This paper, the outcome of a recent international meeting of oculomotor scientists and clinicians with an unusually wide experience of such measurements, sets out a proposed protocol for clinical antisaccade trials: its adoption will greatly enhance the clinical and scientific benefits of making these kinds of measurements.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalVision Research
Publication statusPublished - 24 May 2013

Bibliographical note

Funding Information:
This work was supported by a grant from The Guarantors of Brain, and from Gonville and Caius College, Cambridge, to Professor Carpenter.

Other keywords

  • Antisaccade
  • Latency
  • Protocol
  • Saccade


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